GENTADEX 150 WSP

COMPOSITION
Each gram contains

Gentamycin sulphate: 50 mg

Doxycycline hyclate: 100 mg

DESCRIPTION
GENTADEX 150 WSP is a combination of gentamicin and doxycycline. Gentamicin, an aminoglycoside antibiotic, has bactericidal activity primarily against gram-negative bacteria such as E. coli, Klebsiella, Pasteurella, and Salmonella spp. Doxycycline, a tetracycline antibiotic, is bacteriostatic and effective against a broad range of both gram-positive and gram-negative bacteria, including Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus, and Streptococcusspp., as well as Chlamydia, Mycoplasma, and Rickettsiaspp. Doxycycline inhibits bacterial protein synthesis, while gentamicin works locally within the gastrointestinal tract. Due to its strong affinity for lung tissues, doxycycline is particularly effective for respiratory infections. This combination provides potent antibacterial effects in the gastrointestinal tract, along with rapid systemic absorption for intensive treatment.

INDICATIONS
GENTADEX 150 WSP is indicated for the treatment of infections caused by microorganisms sensitive to gentamicin and/or doxycycline. It is particularly effective for managing gastrointestinal and respiratory tract infections in calves, lambs, pigs, and poultry. This combination antibiotic is a potent solution for treating a wide range of infectious diseases in these animals.

CONTRAINDICATIONS

Do not administer to animals with known hypersensitivity to aminoglycosides and/or tetracyclines.
Avoid use in animals with impaired kidney or liver function.
Not suitable for animals with active microbial digestion, such as ruminants.
Not intended for use in animals producing milk or eggs for human consumption.

SIDE EFFECTS

Hypersensitivity reactions, including gastrointestinal disturbances and alterations in intestinal flora, may occur.
Prolonged use at high doses can lead to neurotoxicity, ototoxicity, or nephrotoxicity.

DRUG INCOMPATIBILITY

Do not administer concurrently with penicillins, cephalosporins, quinolones, or cycloserine, as this may reduce the effectiveness of treatment or increase the risk of adverse reactions.

DOSAGE AND ADMINISTRATION
For oral administration via feed or drinking water:

Poultry: 100 g per 100 liters of drinking water for 3 – 5 days.
Calves, lambs, and kids: 1 g per 20 kg bodyweight, twice daily for 4 – 6 days.
Pigs: 100 g per 100 liters of drinking water for 3 – 5 days.

Mixed with feed, use the product immediately. Mixed with drinking water, use within 24 hours.

WITHDRAWAL PERIOD